Management of hemodialysis catheter-related bacteremia with an adjunctive antibiotic lock solution
نویسندگان
چکیده
منابع مشابه
Minocycline-EDTA lock solution prevents catheter-related bacteremia in hemodialysis.
There is growing concern about the development of antibacterial resistance with the use of antibiotics in catheter lock solutions. The use of an antibiotic that is not usually used to treat other serious infections may be an alternative that may reduce the clinical impact should resistance develop. We conducted a randomized controlled trial to compare a solution of minocycline and EDTA with the...
متن کاملDoes antibiotic lock therapy prevent catheter-associated bacteremia in hemodialysis?
Central venous catheter-related blood stream infection is a major cause of morbidity and mortality in patients with renal disease treated with hemodialysis. Antibiotic lock solutions can be effective in preventing this complication in patients with hemodialysis. Searching in Epistemonikos database, which is maintained by screening more than twenty databases, we identified eight systematic revie...
متن کاملOptimal Approach for the Diagnosis of Hemodialysis Catheter-Related Bacteremia.
Central venous catheter (CVC) use among patients on hemodialysis (HD) remains unacceptably high and is associated with an increased risk of all-cause infection, infection-related hospitalizations, and mortality (1–4). In CVC-dependent patients on HD who present with suspected infection (symptoms of fever, rigors, altered mental status, unexplained hypotension, or CVC exit site purulence) and in...
متن کاملTreatment of catheter-related bacteraemia with an antibiotic lock protocol: effect of bacterial pathogen.
BACKGROUND The standard therapy of dialysis catheter-related bacteraemia involves both systemic antibiotics and catheter replacement. We reported recently that instillation of an antibiotic lock (highly concentrated antibiotic solution) into the catheter lumen after dialysis sessions, in conjunction with systemic antibiotics, can successfully treat many episodes of catheter-related bacteraemia ...
متن کاملUse of antimicrobial catheter lock solutions to prevent catheter-related bacteremia.
Catheter-related bacteremia is an important source of morbidity and mortality in hemodialysis patients. A number of well-designed, controlled, prospective trials using antimicrobial catheter lock solutions to prevent catheter-related bacteremia have shown a dramatic, statistically significant decrease in not only infection but also mortality related to catheter-related bacteremia. Despite evide...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2002
ISSN: 0085-2538
DOI: 10.1046/j.1523-1755.2002.00201.x